Hope S Rugo Selected Research

Letrozole (Femara)

1/2024	Overall Survival With Palbociclib Plus Letrozole in Advanced Breast Cancer.
10/2023	Can We De-escalate Therapy for HER2-Positive Metastatic Breast Cancer?
6/2023	Real-world comparative effectiveness of palbociclib plus letrozole versus letrozole in older patients with metastatic breast cancer.
1/2023	Matching-adjusted indirect comparison of PFS and OS comparing ribociclib plus letrozole versus palbociclib plus letrozole as first-line treatment of HR+/HER2- advanced breast cancer.
1/2021	Comparative effectiveness of first-line palbociclib plus letrozole versus letrozole alone for HR+/HER2- metastatic breast cancer in US real-world clinical practice.
1/2020	Efficacy and safety of palbociclib plus endocrine therapy in North American women with hormone receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer.
1/2020	Biomarker Analyses of Response to Cyclin-Dependent Kinase 4/6 Inhibition and Endocrine Therapy in Women with Treatment-Naïve Metastatic Breast Cancer.
1/2020	Progression-free Survival Outcome Is Independent of Objective Response in Patients With Estrogen Receptor-positive, Human Epidermal Growth Factor Receptor 2-negative Advanced Breast Cancer Treated With Palbociclib Plus Letrozole Compared With Letrozole: Analysis From PALOMA-2.
1/2020	Clinical Significance of Circulating Tumor Cells in Hormone Receptor-positive Metastatic Breast Cancer Patients who Received Letrozole with or Without Bevacizumab.
1/2020	TBCRC 002: a phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormone receptor-positive and HER2-negative breast cancer.

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Hope S Rugo Research Topics

Disease

295	Breast Neoplasms (Breast Cancer) 05/2024 - 12/2003
162	Neoplasms (Cancer) 06/2024 - 12/2003
53	Triple Negative Breast Neoplasms 04/2024 - 01/2010
24	Neoplasm Metastasis (Metastasis) 02/2024 - 01/2008
23	Disease Progression 12/2023 - 09/2012
19	Neutropenia 10/2023 - 06/2013
16	Diarrhea 10/2023 - 01/2017
15	Fatigue 02/2024 - 02/2012
13	Nausea 01/2023 - 02/2013
12	Vomiting 01/2023 - 02/2013
11	Pathologic Complete Response 12/2023 - 01/2020
10	Stomatitis 02/2023 - 06/2004
9	Anemia 01/2022 - 02/2012
8	Pneumonia (Pneumonitis) 01/2023 - 02/2012
8	Brain Neoplasms (Brain Tumor) 06/2022 - 01/2009
8	Circulating Neoplastic Cells 01/2022 - 01/2017
8	Febrile Neutropenia 01/2022 - 10/2013
7	Alopecia (Baldness) 01/2023 - 01/2017
6	Hyperglycemia 01/2024 - 02/2012
6	Hypertension (High Blood Pressure) 10/2018 - 01/2004
5	Exanthema (Rash) 06/2023 - 01/2017
5	Infections 01/2023 - 01/2019
5	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2023 - 01/2021
5	Peripheral Nervous System Diseases (PNS Diseases) 01/2020 - 07/2015
4	Residual Neoplasm 03/2024 - 02/2012
4	Leukemia 01/2021 - 06/2004
4	Proteinuria 01/2016 - 01/2004

Drug/Important Bio-Agent (IBA)

131	Hormones (Hormone)IBA 05/2024 - 04/2007
62	ErbB Receptors (EGF Receptor)IBA 01/2024 - 02/2007
39	palbociclibIBA 04/2024 - 01/2016
35	Trastuzumab (Herceptin)FDA Link 12/2023 - 02/2007
31	Biomarkers (Surrogate Marker)IBA 03/2024 - 01/2008
28	Aromatase InhibitorsIBA 03/2024 - 07/2007
27	Paclitaxel (Taxol)FDA LinkGeneric 12/2023 - 10/2006
25	human ERBB2 proteinIBA 02/2024 - 02/2011
21	taxaneIBA 10/2023 - 02/2005
20	Estrogen ReceptorsIBA 04/2024 - 06/2009
20	Everolimus FDA Link 12/2023 - 06/2009
19	Capecitabine (Xeloda)FDA Link 10/2022 - 02/2005
19	Bevacizumab (Avastin)FDA Link 01/2020 - 01/2004
18	Letrozole (Femara)FDA LinkGeneric 01/2024 - 06/2009
18	Cyclin-Dependent Kinase 4IBA 11/2023 - 02/2016
17	Epidermal Growth Factor (EGF)IBA 05/2024 - 03/2010
16	exemestane (Aromasin)FDA Link 12/2023 - 02/2012
15	Fulvestrant (Faslodex)FDA Link 01/2024 - 02/2016
14	sacituzumab govitecanIBA 05/2024 - 01/2019
13	abemaciclibIBA 04/2024 - 02/2016
13	AnthracyclinesIBA 07/2019 - 02/2005
12	pembrolizumabIBA 12/2023 - 08/2017
11	Gemcitabine FDA Link 10/2022 - 05/2013
11	Carboplatin (JM8)FDA LinkGeneric 10/2022 - 04/2005
11	Estrogens (Estrogen)FDA Link 05/2020 - 04/2007
11	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 01/2004
10	AlpelisibIBA 01/2024 - 01/2018
10	Tyrosine Kinase InhibitorsIBA 02/2023 - 10/2006
10	Lapatinib (GW572016)FDA Link 01/2020 - 02/2007
9	Monoclonal AntibodiesIBA 06/2024 - 01/2004
9	130-nm albumin-bound paclitaxelIBA 11/2021 - 07/2015
8	Immunoconjugates (Immunoconjugate)IBA 02/2024 - 02/2011
8	Phenobarbital (Luminal)FDA Link 12/2023 - 11/2011
8	Ado-Trastuzumab EmtansineIBA 01/2023 - 02/2011
8	B7-H1 AntigenIBA 01/2022 - 08/2017
7	eribulin FDA Link 10/2023 - 09/2017
7	talazoparibIBA 10/2023 - 01/2018
7	Progesterone Receptors (Progesterone Receptor)IBA 09/2023 - 04/2007
7	Immune Checkpoint InhibitorsIBA 01/2023 - 12/2016
7	Vinorelbine (Navelbine)FDA LinkGeneric 10/2022 - 01/2004
7	etirinotecan pegolIBA 01/2022 - 11/2015
7	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022 - 08/2005
7	TOR Serine-Threonine KinasesIBA 01/2020 - 02/2012
6	LigandsIBA 05/2024 - 01/2004
6	Cyclophosphamide (Cytoxan)FDA LinkGeneric 10/2023 - 02/2007
6	neratinibIBA 10/2023 - 05/2019
6	ribociclibIBA 09/2023 - 02/2016
6	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 01/2018
6	ixabepilone (BMS 247550)FDA Link 01/2020 - 06/2013
5	Proteins (Proteins, Gene)FDA Link 05/2024 - 10/2021
5	Circulating Tumor DNAIBA 03/2024 - 01/2018
5	Messenger RNA (mRNA)IBA 12/2023 - 01/2020
5	PlatinumIBA 11/2021 - 06/2015
4	Surface Antigens (Surface Antigen)IBA 02/2024 - 01/2021
4	Irinotecan (Camptosar)FDA LinkGeneric 10/2022 - 01/2019
4	atezolizumabIBA 11/2021 - 11/2018
4	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2021 - 02/2007
4	Progesterone FDA LinkGeneric 01/2020 - 01/2010
4	SteroidsIBA 01/2020 - 01/2016
4	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2020 - 02/2016
4	Palonosetron (Aloxi)FDA Link 01/2019 - 02/2013
4	Angiogenesis InhibitorsIBA 10/2018 - 08/2005
3	AntigensIBA 06/2024 - 01/2015
3	gedatolisibIBA 04/2024 - 01/2023
3	Cell-Free Nucleic AcidsIBA 03/2024 - 01/2021

Therapy/Procedure

158	Therapeutics 06/2024 - 12/2003
121	Drug Therapy (Chemotherapy) 05/2024 - 12/2003
33	Neoadjuvant Therapy 04/2024 - 12/2004
13	Drug Tapering 04/2024 - 08/2005
8	Adjuvant Chemotherapy 06/2022 - 12/2003
7	Aftercare (After-Treatment) 06/2023 - 11/2011
6	Immunotherapy 04/2024 - 01/2021
6	Radiotherapy 02/2024 - 01/2018